This radio program is a weekly series of episodes that provide insights into a broad range of biomedical science topics. We hope these episodes stimulate you to think, question and appreciate how science impacts you and your world.
This Week's Episode
Lyme Disease
You’ve heard of Lyme disease and you may know it’s transmitted by a tick bite. But you many not know much beyond that. If so, this is a good refresher since summer is here and you may be headed outdoors.
That’s right. Plus, ticks are such nasty looking critters; the last thing I’d want is to find one attached to me. If you haven’t seen one up close just check out our website.
They look like something out of the movie – "Alien". They attach by piercing the skin and embedding themselves to feed. You need tweezers to remove them and doing so within 24 hours is key to preventing Lyme disease.
If you don’t, within a week after infection symptoms could appear but they vary making it hard to diagnose. In the classical presentation, you can have fever, headache, muscle and joint pain, plus a rash that resembles a bulls-eye. The problem is some people have no early symptoms.
After days or weeks, the infection can spread throughout the body with pain seemingly moving from joint to joint. It gets even more serious when you have inflammation of the heart and nerves and some even suffer mental changes.
Luckily you can treat this bacterial disease with antibiotics. What’s little known is that there was a safe and effective vaccine but it was withdrawn by the manufacturer in 2002 because of slow sales.
Ticks spread lyme disease by feeding on an infected animal and then biting humans and other animals. But you can do a lot to avoid this by removing woodpiles and leaf debris around your house; clearing thick brush and trees that attract deer and rodents; wearing long sleeves and pants; and using insect repellants containing DEET if you plan on spending a lot of time outdoors.
Tomatoes are one of my favorite foods and now they’re on the "black list" because of the nationwide outbreak of salmonella infections.
Salmonella gastroenteritis is a serious disease, Norbert. Until the source of this contamination is found it would be best to avoid the types of tomatoes responsible.
First recognized in April, the disease has been found in 383 people in thirty states. At least 48 people have been hospitalized and one person in Texas may have died from this. While the reported numbers aren’t huge, Salmonella cases are always under reported so there are likely thousands more.
What’s remarkable was how they were able to narrow this outbreak to a single source since Salmonella gastroenteritis is a common food borne disease in the US.
Also consider there are more than 2000 different types of Salmonella that cause gastroenteritis. The Centers for Disease Control compared the DNA "genetic fingerprints" of bacteria isolated from infected individuals and found they all involve Salmonella serotype Stpaul. This particular Salmonella is relatively rare so this outbreak is unlikely to be a random pattern of disease.
The CDC was able to determine that uncooked tomatoes were the common food consumed by these individuals. This is a nifty piece of detective work by the agency charged to help protect us from disease.
People with Salmonella gastroenteritis get diarrhea, abdominal cramps and fever in 12-72 hours after eating contaminated food. While most people feel like they want to die, they rarely do. But in people with impaired immune systems, the disease can become life threatening. This may be the case for the death in Texas.
Tracking and identifying the source of outbreaks is important for the control of infectious diseases. It is also one of the many reasons why it is important to continue to invest in a vibrant and responsive public health system in the US.
"The outbreak of Salmonella Infections Continues" Since April, 869 persons infected with Salmonella Saintpaul with the same genetic fingerprint have been identified in 36 states and the District of Columbia. These were identified because clinical laboratories in all states send Salmonella strains from ill persons to their State public health laboratory for characterization. The number of ill persons identified in each state is as follows: Arkansas (10 persons), Arizona (41), California (10), Colorado (11), Connecticut (4), Florida (1), Georgia (20), Idaho (3), Illinois (91), Indiana (11), Kansas (14), Kentucky (1), Maine (1), Maryland (29), Massachusetts (21), Michigan (6), Minnesota (2), Missouri (12), New Hampshire (3), Nevada (11), New Jersey (6), New Mexico (90), New York (26), North Carolina (5), Ohio (7), Oklahoma (23), Oregon (10), Pennsylvania (8), Rhode Island (3), Tennessee (6), Texas (346), Utah (2), Virginia (22), Vermont (2), Washington (4), Wisconsin (6), and the District of Columbia (1).
Although the initial epidemiological data strongly suggested that consuming raw tomatoes was associated with illness, the pattern of illnesses now suggests that people eating at restaurants are becoming infected. CDC has broadened its investigation to include foods items that are commonly consumed with tomatoes.
"Identification of a Marker to Predict Prostate Cancer Survival" Prostate cancer will affect 1 in 6 men during their lifetime. The key to surviving prostate cancer are its early diagnosis and whether the cancer has spread to secondary sites in a process called metastasis. Scientists have identified a protein called KLF6 whose detection in prostate cancer cells is indicative of poor survival. Increased levels of this protein is correlated with more rapid metastasis and decreased survival in mice. For more information...
"How Broccoli Prevent Prostate Cancer" Hey guys, your Mom always told you to eat your veggies, especially the broccoli. Well, she was right, but she may not have known why. Science has shown that eating broccoli can help protect you from prostate cancer but no one knew why. A recent study has discovered that men eating .88 pounds of broccoli, but not those men eating the same amount of peas had profound alterations in the expression of their genes. The consumption of relatively low amounts of cruciferous vegetables including broccoli, Brussels sprouts, cauliflower, cabbage, rocket, watercress, garden cress, kale, bok choy, radish, horseradish and wasabi can alter cell signaling pathways. These signaling pathways transmit information through molecular cascades to the nucleus of the cell where gene expression occurs. So listen to Mom. For more information...
"So How Many Calories Are in Your Favorite Alcoholic Drink" The Food Policy Institute at the Consumer Federation of America has published a report that provides information on the calories and carbohydrates in your favorite wine, beer or spirits. That tall cold beer after mowing the lawn on a hot Saturday can involve 98-150 calories in 12 ounces depending on if you prefer light beers or one that is more substantial like Heineken. Wines average about 118 calories per 5 oz. glass, while spirits range from 96-120 calories per 1.5 oz. serving. We haven’t even considered the bar snacks and the calories they add. For more information...